![]() It is used commercially for fumigation, electroplating, mining, chemical synthesis, and the production of synthetic fibers, plastics, dyes, and pesticides. If needed, a second dose (half of the initial dose) may be administered. Hydrogen cyanide (AC) is a chemical warfare agent (military designation, AC). Sodium thiosulfate should be given IV immediately following sodium nitrite administration at a dose of 12.5 g.If needed, a second dose of up to half the previous dose may be given, as long as methemoglobin levels are kept below 35-40%. Intravenous antidotes are indicated for moderate poisoning. A single dose of sodium nitrite is typically enough to raise methemoglobin levels to 20% in an adult. Clinically mild poisoning may be treated by rest, oxygen and amyl nitrite. Once the IV line is in place, amyl nitrite should be discontinued and 10 mL of 3% sodium nitrite (300mg) should be infused IV at a rate of 2.5 - 5.0 mL/min (2-4 mins).Reapply until sodium nitrite can be administered (IV must be in place). Amyl nitrite should be given in alternate intervals of 15 sec followed by 15 sec rest, using a new ampule every 3 minutes. The antidote is also unique because it can be taken orally (current antidotes must be given intravenously) and may be administered up to an hour prior to cyanide exposure. Traces of cyanide have been found in the car of the suspect in a series of cyanide poisonings and traces of an antidote were found in a parcel addressed to her, according to Associate Professor Weerachai Phutdhawong, a lecturer at the Chemistry Department of Faculty of Liberal Arts and Science at Kasetsart University. Break and ampule of amyl nitrite in a handkerchief and hold it in front of the patients mouth/nose.1 Tourniquet & Instructions for Treatment.12 Ampules Amyl Nitrite Inhalants (0.3 mL).2 Vials Sodium Thiosulfate Injection (12.5 g in 50mL of water).2 Ampules Sodium Nitrite Injection (300 mg in10mL of water).
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